Mayo Clinic: $7.1B Revenue, $5.7B Expenses

Mayo Clinic earns a C on the efficiency rubric — the median bucket on the NonprofitTruth scale, indicating performance close to the national midpoint across financial reserves, officer compensation, and revenue consistency. Composite score: 55/100.

Mayo Clinic operates at corporate scale — $7.1B in reported 2022 revenue. At over a billion in annual revenue, nonprofits typically run consolidated operations across multiple states or business lines, and the IRS Form 990 reflects a much larger operational footprint than a typical 501(c)(3). Reserves are the limiting factor: Mayo Clinic carries relatively few months of operating expenses on its balance sheet, which can leave an organization exposed if a major funding source pauses.

Five-year revenue has grown modestly. Mayo Clinic is not expanding rapidly but is not shrinking either; the trajectory is consistent with stable donor and grant relationships. Officer compensation is modest relative to organizational size: Mayo Clinic reports $21.1M in total compensation for current officers and key employees (Form 990 Part IX, line 5) against $7.1B in revenue. The ratio is well within the bands third-party charity raters consider reasonable at this scale. Mayo Clinic is categorized under Health — the largest segment of U.S. nonprofit revenue, dominated by hospitals, hospital systems, and health-research organizations. The financial profile in this category is capital-intensive, with large balance sheets and program service revenue that often dwarfs donations.