Skip to main content
NonprofitTruth

Top-Rated Nonprofits in Illinois 2026

Illinois has 44 nonprofits with $40.5B in combined revenue. The top-rated organization is University Of Chicago Medical Center with an Efficiency Score of 91/100.

Illinois has 44 nonprofits in the IRS Form 990 dataset ranked here by efficiency score. The NonprofitTruth nonprofit efficiency rubric combines financial health / operating reserves (40%), revenue-growth consistency (35%), and officer compensation relative to revenue (25%) into a 0-100 composite.

Reading the ranking: top of the list typically combines healthy operating reserves (the highest-weighted factor) with stable multi-year revenue and reasonable officer compensation. Large hospital and university systems often appear near the top in any state — their scale gives them deep balance sheets and steady revenue. Each nonprofit links to its full Form 990 profile. For donors trying to choose between organizations, the efficiency grade is a useful triage — but the underlying reserve position, the multi-year revenue trend, and the officer-comp ratio matter more than the composite letter on any individual decision.

Top 20 of 44 Nonprofits in Illinois

#OrganizationCategoryRevenueCEO PayScore
1University Of Chicago Medical CenterHealth$2.9B$20.3MA (91)
2Northwestern Memorial HealthcareHealth$9.1B$20.3MA (85)
3Noble Network Of Charter SchoolsEducation$240.9M$1.3MA (82)
4National Louis UniversityEducation$126.8M$1.8MA (82)
5Elevate EnergyEnvironment & Animals$50.9M$297KB (79)
6Rush University Medical CenterHealth$2.7B$33.0MB (78)
7Aurora UniversityEducation$172.8M$1.2MB (78)
8Osf Healthcare SystemHealth$3.4B$17.7MB (76)
9Lewis UniversityEducation$189.0M$1.7MB (75)
10Institute For The International Education Of StudentsEducation$126.7M$3.3MB (75)
11Depaul UniversityEducation$848.4M$8.9MB (73)
12Advocate Health And Hospitals CorporationHealth$6.9B$5.4MB (68)
13Northshore University HealthsystemHealth$2.2B$25.1MB (66)
14Loyola University Of ChicagoEducation$992.7M$10.8MB (66)
15Augustana CollegeEducation$153.9M$1.9MB (66)
16National Board Of Osteopathic Medical Examiners IncArts, Culture & Humanities$32.4M$2.2MC (63)
17University Of ChicagoEducation$4.7B$21.1MC (62)
18Northwestern Memorial HealthcareHealth$2.1B$19.8MC (62)
19Columbia College ChicagoEducation$239.2M$3.8MC (61)
20North Central CollegeEducation$140.1M$2.5MC (60)

Nonprofit financial data for Illinois is sourced from IRS Form 990 filings, which all tax-exempt organizations must file annually.

Frequently Asked Questions

University Of Chicago Medical Center is the top-rated nonprofit in Illinois with an Efficiency Score of 91/100 (Grade A) and $2.9B in annual revenue.

Illinois has 44 nonprofits in our database with a combined $40.5B in total revenue.

The Efficiency Score (0-100, A-F) measures a nonprofit's financial structure based on financial health / operating reserves (40%), revenue-growth consistency (35%), and current-officer compensation relative to revenue (25%), all from IRS Form 990 data. Higher scores indicate stronger financial structure. It does not include a program-spending ratio, which our data source does not provide.

Sources: IRS Form 990

Efficiency Score: financial health / operating reserves (40%), revenue-growth consistency (35%), current-officer compensation ratio (25%). No program-spending ratio is included — total program service expenses are not available from the ProPublica Nonprofit Explorer feed.