Top-Rated Nonprofits in Missouri 2026
Missouri has 25 nonprofits with $19.8B in combined revenue. The top-rated organization is Bjc Health System with an Efficiency Score of 80/100.
Missouri has 25 nonprofits in the IRS Form 990 dataset ranked here by efficiency score. The NonprofitTruth nonprofit efficiency rubric combines financial health / operating reserves (40%), revenue-growth consistency (35%), and officer compensation relative to revenue (25%) into a 0-100 composite.
Reading the ranking: top of the list typically combines healthy operating reserves (the highest-weighted factor) with stable multi-year revenue and reasonable officer compensation. Large hospital and university systems often appear near the top in any state — their scale gives them deep balance sheets and steady revenue. Each nonprofit links to its full Form 990 profile. For donors trying to choose between organizations, the efficiency grade is a useful triage — but the underlying reserve position, the multi-year revenue trend, and the officer-comp ratio matter more than the composite letter on any individual decision.
Top 20 of 25 Nonprofits in Missouri
| # | Organization | Category | Revenue | CEO Pay | Score |
|---|---|---|---|---|---|
| 1 | Bjc Health System | Health | $6.7B | $12.1M | A (80) |
| 2 | American Theatre Guild | Arts, Culture & Humanities | $45.4M | $311K | B (79) |
| 3 | Friends Of The Zoo Inc Of Kansas City Mo | Environment & Animals | $62.5M | $907K | B (78) |
| 4 | Ssm Health Care St Louis | Health | $2.2B | $3.9M | B (77) |
| 5 | Childrens Mercy Hospital | Health | $2.0B | $11.6M | B (76) |
| 6 | Maryville University Of St Louis | Education | $154.6M | $1.9M | B (74) |
| 7 | St Louis University | Education | $1.1B | $5.2M | B (68) |
| 8 | A T Still University Of Health Sciences | Education | $206.3M | $5.0M | B (66) |
| 9 | Webster University | Education | $126.9M | $2.1M | C (63) |
| 10 | Washington University | Education | $5.1B | $24.3M | C (56) |
| 11 | Humane Society Of Missouri | Environment & Animals | $30.8M | $720K | C (55) |
| 12 | Ewing Marion Kauffman Foundation | Education | $173.8M | $0 | C (54) |
| 13 | The Saint Louis Zoo Foundation | Environment & Animals | $63.3M | $0 | C (54) |
| 14 | Saint Louis Symphony Orchestra | Arts, Culture & Humanities | $52.2M | $1.2M | C (54) |
| 15 | Bjc Health System | Health | $1.3B | $31.5M | C (53) |
| 16 | Municipal Theatre Association Of St Louis | Arts, Culture & Humanities | $27.8M | $913K | C (52) |
| 17 | Johnny Morris Wonders Of Wildlife Foundation | Arts, Culture & Humanities | $26.2M | $0 | C (52) |
| 18 | St Louis Art Museum Foundation | Arts, Culture & Humanities | $19.6M | $0 | C (51) |
| 19 | Forest Park Forever Inc | Environment & Animals | $22.5M | $1.3M | C (50) |
| 20 | Lindenwood Education System | Education | $137.7M | $3.5M | D (49) |
Nonprofit financial data for Missouri is sourced from IRS Form 990 filings, which all tax-exempt organizations must file annually.
Frequently Asked Questions
Bjc Health System is the top-rated nonprofit in Missouri with an Efficiency Score of 80/100 (Grade A) and $6.7B in annual revenue.
Missouri has 25 nonprofits in our database with a combined $19.8B in total revenue.
The Efficiency Score (0-100, A-F) measures a nonprofit's financial structure based on financial health / operating reserves (40%), revenue-growth consistency (35%), and current-officer compensation relative to revenue (25%), all from IRS Form 990 data. Higher scores indicate stronger financial structure. It does not include a program-spending ratio, which our data source does not provide.
Efficiency Score: financial health / operating reserves (40%), revenue-growth consistency (35%), current-officer compensation ratio (25%). No program-spending ratio is included — total program service expenses are not available from the ProPublica Nonprofit Explorer feed.