Top-Rated Nonprofits in Massachusetts 2026
Massachusetts has 69 nonprofits with $76.2B in combined revenue. The top-rated organization is Dana Farber Cancer Institute with an Efficiency Score of 87/100.
Massachusetts has 69 nonprofits in the IRS Form 990 dataset ranked here by efficiency score. The LakeQuality nonprofit efficiency rubric combines program-spending ratio (50%), revenue growth consistency (20%), fund reserves (20%), and CEO compensation ratio (10%) into a 0-100 composite.
Reading the ranking: top of the list typically combines strong program-spending discipline (the highest-weighted factor) with stable multi-year revenue and reasonable executive compensation. Large hospital and university systems often appear near the top in any state — their scale lets them keep program ratios high while still investing in infrastructure. Each nonprofit links to its full Form 990 profile. For donors trying to choose between organizations, the efficiency grade is a useful triage — but the underlying program-spending ratio, the multi-year revenue trend, and the comp ratio matter more than the composite letter on any individual decision.
Top 20 of 69 Nonprofits in Massachusetts
Nonprofit financial data for Massachusetts is sourced from IRS Form 990 filings, which all tax-exempt organizations must file annually.
Frequently Asked Questions
Dana Farber Cancer Institute is the top-rated nonprofit in Massachusetts with an Efficiency Score of 87/100 (Grade A) and $3.4B in annual revenue.
Massachusetts has 69 nonprofits in our database with a combined $76.2B in total revenue.
The Efficiency Score (0-100, A-F) measures nonprofit effectiveness based on program expense ratio (50%), revenue growth consistency (20%), fund reserves (20%), and CEO compensation ratio (10%). Higher scores indicate more efficient organizations.
Efficiency Score: program expense ratio (50%), revenue growth consistency (20%), fund reserves (20%), CEO compensation ratio (10%).