| 1 | Mayo Clinic Group Return Health | Health | 86 | $14.0B | 78.0% | A |
| 2 | Fairview Health Services Health | Health | 86 | $4.7B | 78.0% | A |
| 3 | Allina Health System Health | Health | 84 | $5.4B | 78.0% | A |
| 4 | Mayo Clinic Health | Health | 84 | $2.0B | 78.0% | A |
| 5 | Neighborhood Recycling Corporation Environment & Animals | Environment & Animals | 83 | $22.7M | 78.0% | A |
| 6 | Scholarship America Inc Education | Education | 81 | $240.3M | 78.0% | A |
| 7 | Borealis Philanthropy Arts, Culture & Humanities | Arts, Culture & Humanities | 79 | $39.4M | 78.0% | B |
| 8 | Ucare Minnesota Health | Health | 78 | $6.2B | 78.0% | B |
| 9 | Minnesota Land Trust Environment & Animals | Environment & Animals | 78 | $18.9M | 78.0% | B |
| 10 | St Catherine University Education | Education | 77 | $129.6M | 78.0% | B |
| 11 | Twin Cities Public Television Inc Arts, Culture & Humanities | Arts, Culture & Humanities | 75 | $57.8M | 78.0% | B |
| 12 | Minnesota Public Radio Arts, Culture & Humanities | Arts, Culture & Humanities | 74 | $114.0M | 78.0% | B |
| 13 | Center For Energy And Environment Environment & Animals | Environment & Animals | 74 | $24.5M | 78.0% | B |
| 14 | University Of St Thomas Education | Education | 73 | $537.1M | 78.0% | B |
| 15 | Minnesota Historical Society Arts, Culture & Humanities | Arts, Culture & Humanities | 73 | $91.5M | 78.0% | B |
| 16 | Science Museum Of Minnesota Arts, Culture & Humanities | Arts, Culture & Humanities | 72 | $35.1M | 78.0% | B |
| 17 | Hennepin Theatre Tr Arts, Culture & Humanities | Arts, Culture & Humanities | 71 | $45.1M | 78.0% | B |
| 18 | Mayo Clinic Health | Health | 68 | $7.1B | 78.0% | B |
| 19 | Ecmc Group Inc Education | Education | 68 | $5.0B | 78.0% | B |
| 20 | Carleton College Education | Education | 68 | $296.5M | 78.0% | B |
| 21 | Macalester College Education | Education | 68 | $186.4M | 78.0% | B |
| 22 | Minneapolis Society Of Fine Arts Arts, Culture & Humanities | Arts, Culture & Humanities | 68 | $63.9M | 78.0% | B |
| 23 | Walker Art Center Inc Arts, Culture & Humanities | Arts, Culture & Humanities | 68 | $60.7M | 78.0% | B |
| 24 | Guthrie Theatre Foundation Arts, Culture & Humanities | Arts, Culture & Humanities | 68 | $37.4M | 78.0% | B |
| 25 | Gustavus Adolphus College Education | Education | 64 | $150.5M | 78.0% | C |
| 26 | University Of Minnesota Foundation Education | Education | 63 | $428.1M | 78.0% | C |
| 27 | St Olaf College Education | Education | 63 | $251.6M | 78.0% | C |
| 28 | Artspace Projects Inc Arts, Culture & Humanities | Arts, Culture & Humanities | 60 | $29.1M | 78.0% | C |
| 29 | Minnesota Orchestral Association Arts, Culture & Humanities | Arts, Culture & Humanities | 58 | $45.0M | 78.0% | C |