| 1 | Trustees Of The University Of Pennsylvania Education | Education | $9.9B | $53.2M | C |
| 2 | Thomas Jefferson University Education | Education | $1.7B | $21.4M | B |
| 3 | The Childrens Hospital Of Philadelphia Health | Health | $3.4B | $17.6M | A |
| 4 | Drexel University Education | Education | $1.4B | $10.7M | B |
| 5 | Lehigh Valley Hospital Health | Health | $3.2B | $10.6M | A |
| 6 | Bucknell University Education | Education | $379.0M | $8.5M | C |
| 7 | Temple University Of The Commonwealth System Of Higher Educ Education | Education | $1.5B | $8.2M | B |
| 8 | University Of Pittsburgh Education | Education | $3.1B | $7.3M | C |
| 9 | Lafayette College Education | Education | $259.0M | $6.6M | C |
| 10 | Swarthmore College Education | Education | $270.7M | $6.1M | C |
| 11 | Duquesne University Of The Holy Spirit Education | Education | $543.3M | $5.5M | B |
| 12 | Temple University Hospital Inc Health | Health | $2.1B | $5.4M | A |
| 13 | Lehigh University Education | Education | $695.4M | $4.8M | C |
| 14 | Philadelphia College Of Osteopathic Medicine Education | Education | $173.2M | $4.7M | B |
| 15 | Bryn Mawr College Education | Education | $241.8M | $4.4M | C |
| 16 | Milton Hershey School & School Trust Education | Education | $888.2M | $4.4M | C |
| 17 | Miltons S Hershey Medical Center Health | Health | $2.6B | $4.3M | A |
| 18 | Corporation Of Haverford College Education | Education | $211.7M | $4.2M | C |
| 19 | University Of Scranton Education | Education | $257.5M | $4.1M | B |
| 20 | Philadelphia Orchestra Association Arts, Culture & Humanities | Arts, Culture & Humanities | $55.2M | $3.8M | D |
| 21 | Franklin & Marshall College Education | Education | $187.0M | $3.4M | C |
| 22 | Gettysburg College Education | Education | $221.8M | $3.3M | C |
| 23 | Lake Erie College Of Osteopathic Medicine Inc Education | Education | $201.5M | $3.3M | C |
| 24 | Saint Josephs University Education | Education | $636.8M | $3.2M | C |
| 25 | Dickinson College Education | Education | $221.6M | $3.1M | C |
| 26 | Franklin Institute Arts, Culture & Humanities | Arts, Culture & Humanities | $39.6M | $2.9M | D |
| 27 | Temple University Health System Inc Education | Education | $269.9M | $2.8M | B |
| 28 | Whyy Inc Arts, Culture & Humanities | Arts, Culture & Humanities | $48.1M | $2.8M | B |
| 29 | Carnegie Institute Arts, Culture & Humanities | Arts, Culture & Humanities | $73.2M | $2.8M | D |
| 30 | Thomas Jefferson University Hospital Health | Health | $2.6B | $2.6M | A |
| 31 | Arcadia University Education | Education | $155.4M | $2.6M | B |
| 32 | Gannon University Education | Education | $166.0M | $2.5M | A |
| 33 | Philadelphia Museum Of Art Arts, Culture & Humanities | Arts, Culture & Humanities | $114.4M | $2.5M | C |
| 34 | Widener University Education | Education | $243.6M | $2.3M | B |
| 35 | Pennsylvania Cyber Charter School Education | Education | $220.9M | $2.2M | B |
| 36 | Pittsburgh Cultural Trust Arts, Culture & Humanities | Arts, Culture & Humanities | $89.9M | $2.1M | C |
| 37 | Wilkes University Education | Education | $150.8M | $2.0M | B |
| 38 | Muhlenberg College Education | Education | $150.2M | $2.0M | D |
| 39 | York College Of Pennsylvania Education | Education | $140.6M | $2.0M | C |
| 40 | Western Pennsylvania Conservancy Environment & Animals | Environment & Animals | $34.5M | $1.9M | D |
| 41 | Susquehanna University Education | Education | $155.8M | $1.8M | B |
| 42 | Desales University Education | Education | $129.5M | $1.5M | B |
| 43 | Geisinger Medical Center Health | Health | $1.9B | $1.4M | B |
| 44 | National Constitution Center Arts, Culture & Humanities | Arts, Culture & Humanities | $21.6M | $1.3M | D |
| 45 | Zoological Society Of Philadelphia Environment & Animals | Environment & Animals | $43.4M | $1.3M | C |
| 46 | Mercyhurst University Education | Education | $149.3M | $1.2M | B |
| 47 | Pittsburgh Symphony Inc Arts, Culture & Humanities | Arts, Culture & Humanities | $30.8M | $1.2M | D |
| 48 | Zoological Society Of Pittsburgh Environment & Animals | Environment & Animals | $27.6M | $1.0M | C |
| 49 | Commonwealth Charter Academy Charter School Education | Education | $420.8M | $1.0M | B |
| 50 | Artsquest Arts, Culture & Humanities | Arts, Culture & Humanities | $30.9M | $1.0M | B |